The journey from Manali to Nagpur covers about 1500 km. The most practical way is to take a bus to Delhi and then a train or flight to Nagpur. Expect a total travel time of 35 to 40 hours by train.
Total Distance: 1500 km by road, 1200 km air distance.
Take the Grand Trunk Express from Delhi for a direct train connection to Nagpur.
October to March for pleasant weather.