The journey from Jaisalmer to Thiruvananthapuram is a massive trip of over 2700 km. The most practical way is to fly from Jaisalmer or Delhi to Thiruvananthapuram. Driving is possible but extremely long and tiring. This route takes you from the desert to the southern tip of India.
Total Distance: 2750 km driving distance, 2300 km straight-line distance.
Book flights in advance for better rates.
October to March for pleasant weather.