The journey from Guruvayur to Tirupati covers approximately 550 km. You can travel via the NH 544 and NH 71. The journey takes about 11 to 13 hours by road or train. Tirupati is a famous pilgrimage site known for the Venkateswara Temple.
Total Distance: 550 km by road, 450 km air distance.
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| Duration | 12 hours | 13 hours |
| Avg Price | 600-1500 INR | 800-1500 INR |
| Operator | Tirupati Express | KSRTC / APSRTC |
| Route | Thrissur Railway Station to Tirupati Junction | Guruvayur-Coimbatore-Salem-Tirupati |
| Tip | Book tickets well in advance. | The route is long; choose a sleeper bus. |
October to March for pleasant weather.