The journey from Guruvayur to Nellore covers approximately 650 km. You can travel via the NH 16. The journey takes about 13 to 15 hours by road or train. Nellore is a major city on the banks of the Penna River.
Total Distance: 650 km by road, 550 km air distance.
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| Duration | 14 hours | 15 hours |
| Avg Price | 700-1600 INR | 900-1600 INR |
| Operator | Nellore Express | KSRTC / APSRTC |
| Route | Thrissur Railway Station to Nellore Junction | Guruvayur-Chennai-Nellore |
| Tip | Book tickets well in advance. | The route is long; choose a sleeper bus. |
October to March for pleasant weather.