The journey from Ananthapur to Vellore covers approximately 350 km. You can travel via NH 42 and NH 48. Vellore is a major city in Tamil Nadu and is well-connected by rail. The route takes you through the scenic landscapes of Andhra Pradesh and Tamil Nadu.
Total Distance: Driving distance is 350 km; straight-line air distance is 280 km.
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| Duration | 7 hours | 8 hours |
| Avg Price | 300 - 800 INR | 500 - 1200 INR |
| Operator | Seshadri Express | APSRTC/TNSTC |
| Route | Anantapur to Katpadi (Vellore), then local transport. | NH 42 and NH 48 via Chittoor. |
| Tip | Katpadi Junction is the main station for Vellore. | Buses are available from Ananthapur to Chittoor, then to Vellore. |
October to March for comfortable weather.