The journey from Ananthapur to Salem covers approximately 400 km. You can travel via NH 44. Salem is a major city in Tamil Nadu and is well-connected by road and rail. The route takes you through the scenic landscapes of Andhra Pradesh and Tamil Nadu.
Total Distance: Driving distance is 400 km; straight-line air distance is 350 km.
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| Duration | 8 hours | 9 hours |
| Avg Price | 350 - 900 INR | 600 - 1400 INR |
| Operator | Prasanthi Express | APSRTC/KSRTC |
| Route | Anantapur to Bangalore, then local transport to Salem. | NH 44 via Bangalore. |
| Tip | Bangalore is the main hub for onward travel to Salem. | Buses are available from Ananthapur to Bangalore, then to Salem. |
October to March for comfortable weather.